VIP: Dosage & Administration

Part of the VIP Complete Guide

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Dosage Protocols

RouteDoseFrequencyApplication
Intranasal50 mcg/nostril4× dailyCIRS / Shoemaker protocol
Subcutaneous50–100 mcg1–2× dailyResearch protocols

Preparation

VIP is obtained from compounding pharmacies as either intranasal spray or lyophilized powder for injection. For injectable VIP, standard reconstitution with bacteriostatic water applies. Use the peptide calculator for reconstitution volumes.

Timing & Cycles

In the Shoemaker CIRS protocol, VIP is used as the final step after all other interventions are completed and specific biomarker criteria are met. Intranasal VIP is typically used for 30 days with biomarker monitoring. VIP has a very short half-life (~1 minute) requiring frequent intranasal dosing.

Storage

  • Intranasal spray: refrigerate at 2–8°C
  • Lyophilized powder: store at -20°C long-term, 2–8°C short-term
  • Reconstituted: refrigerate, use within 28 days

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Peptides Insider Editorial Team

Our content is reviewed for accuracy and grounded in peer-reviewed research where available. We do not provide medical advice. Always consult a qualified healthcare professional.