VIP: Benefits & Research

Part of the VIP Complete Guide

Partner

Research Peptides

BioLongevity Labs15% Off
Shop Peptides at BioLongevity Labs

We may earn a commission if you purchase through this link, at no extra cost to you.

Anti-Inflammatory & Immunomodulatory

VIP shifts immune responses from Th1 (pro-inflammatory) toward Th2 (anti-inflammatory), generates regulatory T cells, and modulates dendritic cell function. Research demonstrates efficacy in animal models of rheumatoid arthritis, multiple sclerosis, and inflammatory bowel disease.

CIRS Protocol Application

VIP is used as the final step in the Shoemaker protocol for chronic inflammatory response syndrome. After completing preceding steps (cholestyramine, VCS correction, MARCoNS treatment, etc.), intranasal VIP is used to normalize residual biomarker abnormalities including low MSH, elevated TGF-β1, and MMP-9.

Neuroprotective Effects

VIP promotes neuronal survival, stimulates neurite outgrowth, and modulates glial cell function. Research shows neuroprotective effects in models of Parkinson's disease, Alzheimer's disease, and cerebral ischemia through VPAC1/VPAC2 receptor activation.

Frequently Asked Questions

References

  1. Delgado M, et al.. Vasoactive intestinal peptide: a neuropeptide with pleiotropic immune functions. Amino Acids, 2013.

Researching peptides? We did the hard part.

Get our free Peptide Starter Kit — the 5 most researched compounds, simplified into one actionable guide.

Related Guides

Peptides for Weight Loss

Research-backed peptides studied for fat loss and metabolic support.

Peptides for Muscle Growth

Compounds researched for lean mass, recovery, and performance.

Peptides for Healing

Peptides studied for tissue repair, injury recovery, and regeneration.

How to Reconstitute Peptides

Step-by-step guide to safely mixing lyophilized peptides with BAC water.

How to Inject Peptides

Subcutaneous injection technique, site rotation, and sterile handling.

Peptide Reconstitution Calculator

Calculate exact BAC water volumes and dosing for any peptide vial.

PI

Peptides Insider Editorial Team

Our content is reviewed for accuracy and grounded in peer-reviewed research where available. We do not provide medical advice. Always consult a qualified healthcare professional.