TB-500: Dosage & Administration
Part of the TB-500 Complete Guide
TB-500
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TB-500 Dosage Protocols
TB-500 dosing in research typically follows a two-phase approach: a loading phase with higher doses to saturate tissues, followed by a lower maintenance phase.
| Phase | Dose | Frequency | Duration |
|---|---|---|---|
| Loading | 2–2.5 mg | 2× weekly | 4–6 weeks |
| Maintenance | 2–2.5 mg | 1× weekly or biweekly | 4–8 weeks |
The loading phase ensures systemic distribution to injured or inflamed tissues. TB-500's mechanism involves upregulating actin, a cell-building protein, which supports tissue repair throughout the body. The peptide is not site-specific — it circulates systemically and accumulates at sites of injury.
Reconstitution & Preparation
TB-500 typically comes in 2mg or 5mg lyophilized vials:
- 5mg vial + 2mL BAC water = 2.5mg/mL — draw 1mL for a 2.5mg dose
- 2mg vial + 1mL BAC water = 2mg/mL — draw 1mL for a 2mg dose
Use the peptide calculator for exact volumes. See the reconstitution guide for step-by-step instructions.
Timing & Cycle Length
TB-500 timing considerations:
- Time of day: No strict timing requirement. Can be administered at any time
- Full cycle: Loading (4–6 weeks) + maintenance (4–8 weeks) = 8–14 weeks total
- Relation to injury: Research protocols often begin TB-500 as soon as possible after injury for maximum benefit
- Stacking: Commonly researched alongside BPC-157 for complementary healing mechanisms — TB-500 for systemic tissue repair and BPC-157 for localized healing and angiogenesis
Storage
Standard peptide storage applies:
- Lyophilized: -20°C long-term, 2–8°C for months
- Reconstituted: Refrigerate at 2–8°C, use within 28 days
- Avoid freeze-thaw cycles and protect from light
For complete guidelines, see the peptide storage guide.