Semax: Dosage & Administration

Part of the Semax Complete Guide

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Semax Dosage Protocols

ApplicationFormulationDoseFrequency
Cognitive enhancement0.1% nasal spray200–600 mcg total daily2–3 drops per nostril, 3× daily
Neuroprotection1% nasal spray2–6 mg total daily2–3 drops per nostril, 3–4× daily
Research (SC)Reconstituted200–1,000 mcgOnce daily

Administration

Intranasal is the preferred route, providing rapid absorption and potentially enhanced brain delivery via the olfactory pathway. Subcutaneous injection follows standard reconstitution — use the peptide calculator for volumes.

Standard course: 10–14 days. Avoid late evening dosing as Semax can be mildly stimulating.

Semax Variants

NA-Semax and NA-Semax Amidate are modified forms with improved stability. Some researchers use lower doses due to potentially improved bioavailability. These variants lack formal clinical trial data.

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Peptides Insider Editorial Team

Our content is reviewed for accuracy and grounded in peer-reviewed research where available. We do not provide medical advice. Always consult a qualified healthcare professional.