ARA-290: Benefits & Research

Part of the ARA-290 Complete Guide

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Neuropathic Pain Relief

Phase 2 trials demonstrated ARA-290 improved neuropathic pain scores and increased small fiber nerve density in patients with sarcoidosis-associated neuropathy. Corneal confocal microscopy showed measurable nerve fiber regeneration — objective evidence of structural nerve repair.

Tissue-Protective Effects

ARA-290 activates the innate repair receptor (IRR), triggering anti-apoptotic and anti-inflammatory cascades. The IRR is expressed on stressed and damaged cells, making ARA-290's effects selectively targeted to injured tissue rather than healthy cells.

Metabolic Improvements

Studies in type 2 diabetes patients showed ARA-290 improved metabolic control alongside neuropathic symptom relief. The EPO-derived pathway has established connections to metabolic regulation beyond erythropoiesis.

Frequently Asked Questions

References

  1. Brines M, et al.. ARA 290 improves metabolic control and neuropathic symptoms in patients with type 2 diabetes. Mol Med, 2015.

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Peptides Insider Editorial Team

Our content is reviewed for accuracy and grounded in peer-reviewed research where available. We do not provide medical advice. Always consult a qualified healthcare professional.